Schmidt, MD, from Dalhousie University in Halifax, Nova Scotia, and colleagues reported.
In contrast, riding in a car carries a risk of six deaths per 100 million trips for children 14 years or younger and 40 deaths per 100 million trips for children ages 15 to 19, according to the study published online in .
Administering sedatives to children to facilitate performing therapeutic or diagnostic procedures is a growing practice in hospital and outpatient settings.
Procedures for which sedatives are given include diagnostic imaging studies, laceration repair, foreign body removal, spinal taps, and orthopaedic procedures.
"MRI with contrast enhancement therefore does not meet the minimal-risk standard," when compared with the rate of anaphylaxis from vaccinations, Schmidt and colleagues wrote.
To have comparators with which to gauge the risks associated with MRI scans, the authors examined systematic reviews of the risks from several "everyday" activities of healthy children.
After you come to the hospital for your child’s test or treatment, a nurse or doctor will check your child.
Based on such continuous evaluation, the patient is described as being in one of the following states of sedation: 1) anxiolysis, 2) mild sedation, 3) moderate sedation, 4) deep sedation, 5) general anesthesia.
A collaborative effort by the American Academy of Pediatrics (AAP), American Society of Anesthesiologists (ASA), and the Joint Commission on Accreditation of Healthcare Organizations (JCAHO) has produced comprehensive standards for safe sedation practice.
[1-4] The new guidelines stress that the level or score referring to the patient’s depth of sedation is independent of drug choice, route of administration, or the intended level of consciousness.
"MRI can therefore meet the minimal-risk standard from the point of view of physical harm," which ethics review boards use to determine if a clinical study can proceed, the researchers wrote.
However, the risk of anaphylaxis from MRI contrast agents is 7.5 per 100,000 doses, compared with a risk of 1.53 per one million doses with MMR vaccination and 0.65 per one million doses for any vaccination.